Smallpox - (Variola, variola major - Lat.Smallpox - Engl., Pocken, Blatern - it., Variol - franz.) - An acute viral disease, which in typical cases, characterized by general intoxication, fever, rashes on the peculiar skin and mucous membranes, consistently pa*sing the stage of spots, bubbles, pustules, crusts and scars.Causes of smallpox pathogen is a virus of smallpox, is well preserved during drying.The virus enters the body through the mucous membranes of the upper respiratory tract.Hematogenically infected epithelium, where there is duplication, which causes the development of exanthema and enanthema.May develop infectious-toxic shock.For severe hemorrhagic syndrome characterized.Symptoms during.The incubation period lasts 5-15 days (usually 10-12 days).The disease begins acutely.With a fever the body temperature (40 В° C and above).Patients concerned about the weakness, headache, back pain, sacrum, less nausea, vomiting, abdominal pain.Skin of the face, neck and chest hyperemic, injected scleral vessels.May receive the "predictive" evanescent rash.At the 4 th day of the disease decreased body temperature, some patients feel better, and at the same time there is a characteristic for smallpox rash.Elements of the rash are the spots that turn into papules, vesicles and then to the 7-8-th day of the disease - a pustule.By this time the temperature rises again and the patient's condition worsens.On the 14 th day of illness the pustules turn into crusts, which remain after the defection of scars.Severe forms include confluent smallpox, and hemorrhagic (black) smallpox.In vaccinated smallpox mild (vaccinella) sometimes resembles chickenpox.Complications: encephalitis, pneumonia, eye damage.The diagnosis of smallpox should be necessarily confirmed by laboratory tests.Clinical manifestations of the disease are only the basis for the preliminary diagnosis and taking the material for specific research.Differentiate from monkey pox, varicella (chicken pox, see).Treatment of Smallpox Therapeutic efficacy of smallpox gamma globulin (6.3 ml intramuscularly) and metisazona (0,6 g, 2 times a day for 4-6 days.) Low.For the prevention and treatment of secondary purulent infection Antibiotics (oksalin, methicillin, erythromycin, tetracycline).Bed mode.Oral Care (washing of 1% solution of sodium bicarbonate, before eating 0,1-0,2 g anestezina).In the eyes instilled 15-20% solution of sodium sulfatsil.Elements of the rash cuticles 5-10% solution of pota*sium permanganate.With moderate forms of mortality 5-10%, with the drain - about 50%.
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